35 workers under the age of 35 with scientific and technological innovation announced: wanleixue, Xihu University

On December 10, the 2020 China region list of “35 people under 35 years old in technological innovation” was announced in Shaoxing City, Zhejiang Province. This is the fourth time that the list of “MIT Technology Review innovators under 35” of the global youth science and technology innovation talent list has landed in China. < p > < p > the selected representatives of the scientific research community are Wan Ruixue, a West Lake scholar at West Lake University, who has revealed the molecular mechanism of RNA splicing, Yu Xinge, assistant professor of Biomedical Engineering, City University of Hong Kong, who developed ultra-thin skin, and Yang Yihao, a hundred researchers of Zhejiang University who first experimented with the realization of three-dimensional optical topological insulators. < p > < p > the candidates in the field of scientific innovation include Li Yifan, CEO of Hesai technology, who is committed to the research and development of automatic driving lidar products, and he Ting, the founder and CEO of Beijing Yimiao Shenzhou Pharmaceutical Technology Co., Ltd., who independently develops gene cell drug technology platform. Founded in 1899, it is one of the oldest technology and business think tanks and media in the world. Since 1999, 35 young scientific and technological innovation talents under the age of 35 have been selected every year. Previous winners include well-known AI scholar Wu Enda, apple chief designer Jony ive, and gene editing technology inventor Zhang Feng. < p > < p > in 2017, the list was officially introduced into China, and previous winners include Lu Chaoyang, Professor of China University of science and technology, and Xu Bing, co-founder of Shangtang technology. < / P > < p > in this year’s list, there are pioneers who are constantly searching for the boundary of human science, visionaries who have insight into the direction of technological change, inventors who are constantly inspired, and entrepreneurs who actively promote the implementation of cutting-edge technologies, and people-oriented humanistic care people. < / P > < p > the following is the list of winners of “35 scientific and technological innovations under the age of 35” in China in 2020: < / P > < p > the winners have made outstanding contributions in the field of experimental technology innovation and physical properties research of novel two-dimensional materials, and are committed to in-depth research on two-dimensional materials by integrating optical, micromachined devices and electrical transport measurement. < p > < p > he developed a set of micron scale Fourier transform photoelectron spectroscopy technology, using this new technology for the first time to observe the electric field adjustable exciton in double-layer graphene. In addition, he observed the valley Hall effect in graphene for the first time in his continuous research on graphene, which provided a new idea for the study of topological state and energy valley physics in graphene. In addition, he initiated the study of graphene plasma, which proved the existence and basic physical properties of plasma in graphene. These innovative explorations of graphene physical research and application prospects have great pioneering significance, and extend the development of graphene in new infrared optical and optoelectronic devices, basic materials of energy Valley electronics, terahertz and other technical directions. < / P > < p > the laureate received his Ph.D. in physics from the University of California, Berkeley in 2015, and then worked as a postdoctoral fellow at the cafrey Institute of nanoscience and the Institute of atomic and solid state physics at Cornell University. Reason for award: through the high-resolution structure analysis of splicing molecular machine, the research reveals one of the most basic and important life processes in eukaryotic cells: the molecular mechanism of RNA splicing. < / P > < p > the research of the winners obtained complete splicing structure with a resolution of 3.6 a, which is the first splicing structure with near atomic resolution in the world, and analyzed the near atomic resolution three-dimensional structure of all fully assembled spliceosomes and one pre assembled complex, which clearly clarified the molecular mechanism of RNA splicing and laid a foundation for the treatment of related diseases. From the perspective of structural biology, the winners have clarified the close relationship between structural biology and human body and diseases through basic biological research. Therefore, it has great scientific significance and research value. At the same time, the research on the structure and dynamic changes of spliceosome revealed its working mechanism from the molecular and near atomic level, thus revealing the pathogenesis of related diseases, guiding the treatment of diseases and drug research and development. < / P > < p > the laureate obtained his Ph.D. in 2017 from the school of medicine of Tsinghua University, and then carried out research as a postdoctoral in the school of medicine of Tsinghua University and the advanced innovation center of structural biology of Tsinghua University. < / P > < p > reason for winning the prize: bota bio, which has been deeply cultivated in the field of synthetic biology, uses the solutions of “integration”, “automation” and “modularization” to efficiently and accurately transform, edit and screen target microorganisms with high flux and efficiency. < / P > < p > the winners received their doctorates in medical engineering and medical physics from Harvard Massachusetts Institute of technology in 2016. The company founded in 2019 built enzyme engineering, strain engineering and fermentation process engineering platform based on calculation, covering three technical paths of enzyme catalysis, biotransformation and total biosynthesis to meet the market demand of different industrial biotechnology. < p > < p > from the perspective of engineering thinking, the winners introduced the concepts of gene transformation, component design and assembly, realized the systematization and intellectualization of enzyme engineering and strain engineering, and committed to opening up new technical paths for traditional chemical industry. < / P > < p > starting from the bottom, bota bio has built a “new infrastructure” for biosynthesis through four technical sectors: intelligent experimental design, automatic platform and process, diversified database accumulation, real-time feedback and prosecution. < / P > < p > reason for award: the winners have made a series of groundbreaking achievements in quantum computing and quantum networks. They have manipulated single atoms, electrons and photons with cutting-edge quantum technology, and built a future quantum information technology platform in the micro world. < / P > < p > the winners creatively used the scanning tunneling microscope (STM) technology to realize nano scale chip processing, which can be used to prepare single atom, single electron quantum devices and artificial quantum materials, and can realize single atom scale quantum computing, laying a solid foundation for large-scale scalable silicon-based quantum computing. He successfully placed two phosphorus quantum dots on a 13 nanometer space with single atom precision, and realized the first high-speed two bit gate, 800 picosecond root exchange gate, on a silicon-based quantum chip. < p > < p > based on GaAs quantum dots, the winners and other members of the research team used the wave color sampling scheme of photons and the new multiphoton interferometer to realize the first quantum computer’s surpassing the first electronic tube computer ENIAC and the first transistor computer tradic. < / P > < p > the winners have realized the quantum state transfer from single photon to single electron, developed a new set of single photon frequency bit control and measurement scheme, verified the entanglement between single photon and electron, and transferred the quantum information of photon to electron spin 5 meters away, which is an important breakthrough in solid-state quantum network research. < / P > < p > the laureate obtained his Ph.D. in physics from the University of science and technology of China in 2015. Later, as a postdoctoral, he conducted research in Hefei National Research Center for micro scale material science of University of science and technology of China and Australian Center for quantum computing and communication technology, University of New South Wales. The bio inorganic hybrid system developed by the winners can use solar energy to synthesize bio organic fertilizer. It is a bio inorganic hybrid system in artificial photosynthesis, which is based on the synergy of materials science and biology. It designs a device that mimics the function of plants, collecting solar energy to generate electricity, which then decomposes water into oxygen and hydrogen, and bacteria in the water convert hydrogen and carbon dioxide and nitrogen in the air into bio fertilizer or fuel. < / P > < p > he hopes that the future application scenario will be in everyone’s home, where they can synthesize complex compounds that people need, such as fertilizers, fuels and drug molecules, without leaving home. < p > < p > starting from his graduate work, his work has made us realize that effective assembly and combination of inorganic materials and biocatalysts can achieve more efficient synthesis of chemical products from sunlight than photosynthesis in nature. This pioneering work provides us with a possible means to achieve sustainable development of the chemical industry. This will help us to achieve a green society for a long time. < / P > < p > the laureate received his Ph.D. in chemistry from the University of California, Berkeley in 2013, and subsequently conducted research at Nanyang Polytechnic University and Harvard University as postdoctoral students. < / P > < p > reason for award: by integrating structural biology and cell biology research methods, the infection process of influenza, Ebola, Zika, Lassa and other important viral infectious diseases has been deeply studied, and a series of important progress has been made. < / P > < p > the winners revealed the molecular mechanism of Ebola virus invading host cells, discovered new targets designed by antiviral inhibitors, and confirmed for the first time the existence of the fifth mechanism of viral membrane fusion stimulation at the molecular level, which is a great breakthrough in the field of Virology. < / P > < p > the winners first revealed the regulation mechanism of RNA synthesis by different RNA promoters binding conformation during the RNA replication process of influenza virus genome, and revealed the working mechanism of sand virus polymerase at the molecular level for the first time, and found that there was a similar 3 ‘RNA in the segmented negative strand RNA virus polymerase of influenza virus, sandvirus and bunyavirus The terminal binding site can be used as a new target for the development of broad-spectrum antiviral drugs. < / P > < p > the winner obtained his doctorate in the Institute of Microbiology, Chinese Academy of Sciences in 2011. Later, he worked as an assistant researcher and associate researcher in Beijing Institute of life sciences, Chinese Academy of Sciences. In 2016, he returned to the Institute of Microbiology, Chinese Academy of Sciences to establish a research group. < p > < p > reason for award: the winner has solved several key problems of integrated optical chip and soliton frequency comb, successfully constructed ultra-low loss optical microcavity with integrated silicon nitride material, and opened up the whole industrial production process from design simulation to packaging test. The winner has successfully developed the smallest and most compact soliton micro comb optical chip module in the world, creating the world’s lowest record of 0.5dB loss per meter of optical path. Based on this, it has realized many technical applications such as microwave signal generation, high-speed integrated acousto-optic modulation and laser self injection locking. It also uses deep ultraviolet step lithography, etching, chemical vapor deposition, chemical mechanical polishing and other technologies for the fabrication of silicon nitride waveguides. The loss of the chip waveguide produced is far lower than that of the traditional nano processing technology, which makes large-scale commercial production possible. In addition, the integrated frequency comb based on silicon nitride microcavity developed by the winners is a key module for the construction of high-purity communication light source and ultra-low phase noise microwave oscillator, which can be widely used in the future integrated radar and information network. The achievements of the winners create more possibilities for the generation, processing and detection of optical information in the whole chip in the future, and enable the integrated micro cavity optical frequency comb to be applied in some emerging fields. In addition, breakthroughs are expected to be achieved in key technology fields such as communication, microwave, lidar, quantum computing, and chip integrated optical atomic clock. < / P > < p > the winner once studied physics in junior class of University of science and technology of China. In 2016, he graduated from Erlangen Nuremberg University in Germany and obtained his doctor of Science degree from Federal Institute of technology in Lausanne, Switzerland in 2020. Reasons for award: